Quinidine 是一种抗心律失常剂，也是 K+通道的有效阻断剂，其IC50值为 19.9 μM。它是一种选择性细胞色素 P450db 的有效抑制剂，也可研究疟疾。

Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.

Quinidine blocks the voltage-gated sodium (Nav) channel Nav1.5 in a use-dependent manner.It decreases the amplitude and duration of action potentials in isolated canine ventricular myocytes[1].

56-54-2

C20H24N2O2

324.424

奎尼丁;奎宁树

DMSO:50 mg/mL (154.12 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years