Galangin 3-methyletHER 是一种来源于高良姜根茎的天然黄酮，具有抗菌活性，抑制胰腺脂肪酶。

GALANGIN-3-METHYLETHER has antibacterial activity, it has inhibitory effects on Pseudomonas aeruginosa. GALANGIN-3-METHYLETHER has hypolipidemic activity, the action is due to the inhibition of pancreatic lipase.

GALANGIN-3-METHYLETHER markedly reduced the viability of Leishmania amastigotes.

L. amazonensis amastigotes were maintained and cultured axenically .Washed parasites were resuspended in RPMI-1640 medium supplemented with 4% fetal calf serum, pH 5.0, and incubated at 33 C for 18 h with crude extracts (1 mg/mL) or isolated compounds(GALANGIN-3-METHYLETHER) (0.014, 0.084, 0.5, and 1.0 mg/mL) dissolved in dimethyl sulfoxide (DMSO)/RPMI-1640 (1:99).?The amastigote viability was assessed colorimetrically by the reduction of a tetrazolium salt (MTT) as.?Absorbances were expressed as percentages relative to untreated controls.?Amphotericin B (0.02 mg/mL) was used as the positive control and DMSO/RPMI-1640 (1:99) as negative control.?The bioassays were carried out in triplicate.

6665-74-3

C16H12O5

284.267

GALANGIN-3-METHYLETHER;高良姜素-3-甲醚;高良姜素 3-O-甲醚;3-Methylgalangin

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years