Alpinetin 是从草豆蔻中分离得到的一种黄酮类天然产物,能够活化PPAR-γ,具有抗炎、抗菌活性。它通过抑制增殖、调节 BCL-2 家族和 XIAP 表达、释放细胞色素 c 和激活 Caspase 具有很强的抗肝癌和胰腺癌细胞作用。
产品描述
Alpinetin has antibacterial activity.Alpinetin has anti-inflammatory activity.Alpinetin can enhance the sensitivity of HepG2 hepatoma cells to the chemotherapeutic agent CDDP. Alpinetin has strong anti-hepatoma and pancreatic cancer cells effects, by inhibiting proliferation , regulating of the Bcl-2 family and XIAP expression, releasing of cytochrome c and activating caspases.
Cas No.
36052-37-6
分子式
C16H14O4
分子量
270.28
别名
山姜素;(-)-alpinetin
储存和溶解度
DMSO:49 mg/mL(181.3 mM)
Chloroform, Dichloromethane, Ethyl Acetate, Acetone:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years