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Beta-mangostin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Beta-mangostin图片
CAS NO:20931-37-7
包装与价格:
包装价格(元)
5 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
beta-倒捻子素
β-Mangostin
产品介绍
Beta-mangostin是存在Cratoxylum arborescens中的一种氧杂蒽酮类天然产物,有抗癌和抗菌活性,对结核分枝杆菌的MIC值为 6.25 μg/mL。它在体外有抗疟活性,对恶性疟原虫的IC50值为 3.00 μg/mL。

产品描述

Beta-Mangostin (β-Mangostin) is a xanthone compound with antibacterial and antimalarial activities. Beta-Mangostin (β-Mangostin) present in Cratoxylum arborescens and exhibits antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 6.25 μg/mL. Beta-Mangostin possesses in vitro antimalarial activity against Plasmodium falciparum, with an IC50 of 3.00 μg/mL. beta-Mangostin has potent anticancer activity against various cancers (such as hepatocellular carcinoma, leukaemic).

体外活性

Beta-Mangostin activates the intrinsic apoptosis pathway through reactive oxygen species with downregulation of the HSP70 gene in the HL60 cells associated with a G0/G1 cell-cycle arrest[2].

Cas No.

20931-37-7

分子式

C25H28O6

分子量

424.49

别名

beta-倒捻子素;β-Mangostin

储存和溶解度

DMSO:24 mg/mL (56.53 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years