Beta-mangostin是存在Cratoxylum arborescens中的一种氧杂蒽酮类天然产物，有抗癌和抗菌活性，对结核分枝杆菌的MIC值为 6.25 μg/mL。它在体外有抗疟活性，对恶性疟原虫的IC50值为 3.00 μg/mL。

Beta-Mangostin (β-Mangostin) is a xanthone compound with antibacterial and antimalarial activities. Beta-Mangostin (β-Mangostin) present in Cratoxylum arborescens and exhibits antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 6.25 μg/mL. Beta-Mangostin possesses in vitro antimalarial activity against Plasmodium falciparum, with an IC50 of 3.00 μg/mL. beta-Mangostin has potent anticancer activity against various cancers (such as hepatocellular carcinoma, leukaemic).

Beta-Mangostin activates the intrinsic apoptosis pathway through reactive oxygen species with downregulation of the HSP70 gene in the HL60 cells associated with a G0/G1 cell-cycle arrest[2].

20931-37-7

C25H28O6

424.49

beta-倒捻子素;β-Mangostin

DMSO:24 mg/mL (56.53 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years