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Pallidol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:105037-88-5
包装与价格:
包装价格(元)
5 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍

产品描述

Pallidol is a potent and selective singlet oxygen quencher in aqueous systems, it may be used in singlet oxygen-mediated diseases as a pharmacological agent.

体外活性

Pallidol is a naturally occurring resveratrol dimer from red wine with antioxidant and antifungal activities. METHODS AND RESULTS:In this report, with the use of the EPR spin-trapping technique, the scavenging and quenching effects of Pallidol on reactive oxygen species (ROS) were investigated. The results demonstrated that Pallidol showed strong quenching effects on singlet oxygen at very low concentrations, but it was ineffective to scavenge hydroxyl radicals or superoxide anions. Further kinetic study revealed that the reaction of Pallidol with singlet oxygen had an extremely high rate constant (k(a)=1.71x10(10)). CONCLUSIONS:Therefore, Pallidol is a potent and selective singlet oxygen quencher in aqueous systems. It may be used in singlet oxygen-mediated diseases as a pharmacological agent, which may contribute to the health beneficial effects of red wine.

Cas No.

105037-88-5

分子式

C28H22O6

分子量

454.48

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years