Cyanidin Chloride 是一种花青素的亚类，具有抗氧化和抗癌活性。它能够抑制破骨细胞形成，羟基磷灰石吸收和 NF-Κb 配体 (RANKL) 诱导的破骨细胞标记基因表达的受体激活。

Cyanidin Chloride, the main phenolic antioxidant in the grape (Vitis vinifera), in particular in the liposomal forms, could be used for treatment of diabetes mellitus complications.

Cyanidin Chloride inhibits RANKL-induced NF-κB activation, suppresses the degradation of IκB-α and attenuates the phosphorylation of extracellular signal-regulated kinases (ERK).?In addition, Cyanidin Chloride abrogated RANKL-induced calcium oscillations, the activation of nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1), and the expression of c-Fos.?Further.Cyanidin Chloride protects against ovariectomy-induced bone loss in vivo.

528-58-5

C15H11ClO6

322.7

DMSO:16 mg/mL (49.58 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years