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Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:56317-05-6
包装与价格:
包装价格(元)
5 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍

产品描述

Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside is an α-glucosidase inhibitor with IC50 values between 0.6 and 22.4 μM.

体外活性

Six species of Myrcia , commonly known as 'insulin plants' in Brazil, were assessed for their potential as functional foods. METHODS AND RESULTS: Thus, dual high-resolution α-glucosidase/PTP1B inhibition profiling and HPLC-HRMS-SPE-NMR analysis were used to identify the antidiabetic constituents of the crude ethyl acetate extract of M. rubella Cambess. A total of 31 compounds were identified, including seven α-glucosidase inhibitors with IC 50 values between 0.6 and 22.4 μM: 4,5-dicaffeoylquinic acid, isoquercitrin, quercetin-3- O -β- d -glucuronide, Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside, quercetin-3- O -(6'-malonyl)-glucopyranoside, quercetin-3- O -(6'-(E )-feruloyl)-β- d -glucopyranoside, and quercetin-3- O -(2'-(E )-sinapoyl)-glucopyranoside as well as three strong PTP1B inhibitors with IC 50 values between 0.4 and 3.1 μM: kaempferol-3- O -α- l -rhamnoside, astragalin, and arjunolic acid. CONCLUSIONS: These results show that M. rubella is a potential bifunctional food for management of type 2 diabetes.

Cas No.

56317-05-6

分子式

C28H24O15

分子量

600.48

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years