alpha-Cyperone 与 IL-6, COX-2, Cdc42, Nck-2, Rac1 的表达下调相关,从而能够抑制炎症反应。

1. Alpha-Cyperone is a promising inhibitor of Hla production by S. aureus and protects lung cells from this bacterium. 2. Alpha-Cyperone significantly inhibited PGE2 production by suppressing the LPS-induced expression of inducible COX-2 at both the mRNA and the protein levels , downregulated the production and mRNA expression of the inflammatory cytokine IL-6. 3. Alpha-Cyperone inhibited actin cytoskeleton polymerization induced by APEC-O78 through down regulating the expression of Nck-2, Cdc42 and Rac1.

473-08-5

C15H22O

218.34

α-Cyperone;α-香附酮;(+)-α-Cyperone

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years