D-Menthol 是药物和商业产品中的一种常见化合物,也是一种流行的香烟添加剂,它可以减弱细胞体和神经突中 α±7 介导的 Ca 2+ 瞬变,表明薄荷醇以非竞争性方式抑制 α±7-nACh 受体.
产品描述
D-Menthol is a common compound in pharmaceutical and commercial products and a popular additive to cigarettes, it attenuates α±7 mediated Ca 2+ transients in the cell body and neurite, suggests that menthol inhibits α±7-nACh receptors in a noncompetitive manner.
体外活性
The algal biomass and the intracellular and extracellular MCY concentrations were evaluated during 5d incubation. After the D-Menthol exposure, the dry weight of the cells gradually decreased; the decrease in the dry weight after 5d exposure was 29, 12, and 2mgL(-1) when the initial cell densities were 1.4x10(7), 1.2x10(6), and 2.9x10(5)cellmL(-1), respectively. The results indicate that the D-Menthol exposure inhibited the cellular growth, thus also inhibiting the increase of the total MCY concentration. In the presence of D-Menthol, the intracellular MCY was gradually released into the medium after the cell lysis.
Cas No.
15356-60-2
分子式
C10H20O
分子量
156.27
别名
Menthol;(+)-MENTHOL;D-薄荷醇
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years