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Sclareolide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Sclareolide图片
CAS NO:564-20-5
包装与价格:
包装价格(元)
50 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
Norambreinolide
香紫苏内酯
产品介绍
Sclareolide 是一种从Salvia sclarea的花中分离得到的天然产物,具有抗菌和细胞毒性作用。

产品描述

Sclareolide is a sesquiterpene lactone natural product derived from various plant sources including Salvia yosgadensis, Salvia sclarea, and cigar tobacco. It is a close analog of Sclareol, a plant antifungal compound.

体内活性

Sclareolide被用于化妆品香料,尽管无临床证据支持,其最近还是被当作减肥品销售。

激酶实验

Telomerase activity assay: The telomerase activity is measured by the TRAP assay using the TRAPez Telomerase Detection Kit, which includes primers of a 36-bp internal control (IC) for quantifying the amplification of telomerase activity within a linear range close to 2.5 logs. For RNase treatment, 10μL of extract are incubated with 1μg of RNase at 37 °C for 20 minutes. The products of the TRAP assay are resolved by electrophoresis in a nondenaturing12% PAGE in a buffer containing 0.5 × Tris–borate EDTA and detected by autoradiograph. For quantification of TRAP products, the dried gels are exposed to Fuji Imaging Plate at room temperature. Results are corrected for background, and a standard value of 100 is given to the untreated control cell signal. Signal intensities of Costunolide-treated cells are compared to the standard and are expressed as a fraction of the maximum value of 100. [1]

Cas No.

564-20-5

分子式

C16H26O2

分子量

250.38

别名

Norambreinolide;香紫苏内酯

储存和溶解度

Ethanol:47 mg/mL (187.7 mM)
H2O:<1 mgml
DMSO:47 mg/mL (187.7 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years