OrIDOnin是从Rabdosia rubescens中得到的二萜，是一种Akt抑制剂，对 Akt1 和 Akt2 的IC50值分别为 8.4 和 8.9 μM，具有抗菌、抗炎、抗肿瘤等功效。

Oridonin is a diterpenoid isolated from Rabdosia rubescens with anti-tumor, anti-bacterial and anti-inflammatory effects. It acts as an inhibitor of AKT, with IC50s of 8.4 and 8.9 μM for AKT1 and AKT2.

LD50: Mice 35-40 mg/kg. [4]

28957-04-2

C20H28O6

364.438

Isodonol;NSC-250682;冬凌草甲素;Rubescensin A;Rubescenin

H2O:<1 mgml
Ethanol:28 mg/mL (76.83 mM)
DMSO:72 mg/mL (197.57 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years