Platicodigenin 是从桔梗中分离出的桔梗素,在体外对 HSC-T6 细胞系具有抗增殖活性。
产品描述
Platycodigenin isolated from platycodon grandiflorum, has in vitro anti-proliferative activity against the HSC-T6 cell line.
体外活性
Two new oleanane-type triterpenoids, named platycodonoids A and B (1, 2), together with five known saponins, including platycodin D (3), deapioplatycodin D (4), 3-O-β-D-glucopyranosyl polygalacic acid (5), 3-O-β-D-glucopyranosyl Platycodigenin (6) and polygalacin D (7), were isolated from the roots of Platycodon grandiflorum. METHODS AND RESULTS: On the basis of spectral data and chemical evidence, the structures of the new compounds were elucidated as 2β,3β,23,24-tetrahydroxy-28-nor-olean-12-en-16-one (1) and 2β,3β,23,24- tetrahydroxy-28-nor-olean-12-en-16-one-3-O-β-D-glucopyranoside (2). Compounds 1-7 were evaluated for their in vitro anti-proliferative activity against the HSC-T6 cell line.
Cas No.
22327-82-8
分子式
C30H48O7
分子量
520.7
别名
Platycodigenin;桔梗皂苷元
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years