Esculentoside A 是一种三萜皂苷，从商陆根部分离得到。它在具有抗炎活性，对环氧合酶-2 具有选择性抑制活性。它通过抑制NF-Κb和丝裂原活化蛋白激酶信号通路抑制 LPS 诱导的急性肺损伤中的炎症反应。

Esculentoside A can suppress inflammatory responses in LPS-induced ALI through inhibition of the NF-κB and mitogen-activated protein kinase signaling pathways. Esculentoside A may be useful for the treatment of autoimmune disease through modulation on T cell-mediated adaptive immunity. Esculentoside A may play significant roles in the treatment of BXSB mice through modulation of inflammatory cytokines, inhibition of renal cell proliferation and induction of apoptosis.

65497-07-6

C42H66O16

826.974

DMSO:120.9 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years