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1,3,6-Tri-O-galloyl-beta-D-glucose
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
1,3,6-Tri-O-galloyl-beta-D-glucose图片
CAS NO:18483-17-5
包装与价格:
包装价格(元)
5 mg电议
10 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
1,3,6-Tri-O-galloyl-β-D-glucose
1,3,6-Tri-O-galloylglucose
1,3,6-三没食子酰葡萄糖
1,3,6-三-O-3,4,5-三羟基苯甲酰-BETA-D-葡萄糖
产品介绍
1,3,6-Tri-O-galloyl-beta-D-glucose 是一种酚类化合物,分离自BlACK Walnut Kernels 中。

产品描述

1,3,6-Tri-O-galloyl-beta-D-glucose is a phenolic compound in Black Walnut Kernels. It shows anti-inflammatory activity.

体外活性

The compounds were isolated by silica gel column chromatography, Sephadex LH-20 column chromatography and ODS column chromatography.Their structures were elucidated by spectral analyses and physicochemical properties. The anti-inflammatory activities of selected isolated compounds were evaluated as inhibitory activities against lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW264.7 cell lines by Griess reaction. Eight compounds were obtained from n-butanol fraction oi Mangifera indica L. seed kernel, whose structures were elucidated as 4-O-ethylgallic acid (1), gallic acid (2), citric acid(3), 1,2,3,4,6-penta-O-galloylglucose(4),1,3,6-Tri-O-galloylglucose(5), hyperoside(6), quercetin-3-O-rhamnopyranoside(7), and mangiferin(8). Compounds 1, 2 and 4-8 exhibited potent inhibitory effect on NO production in LPS-induced macrophages, especially compounds 6 and 8 showed the best inhibitory activity with IC50 values of 16.5 and 19.5 μmol·L-1, respectively.

Cas No.

18483-17-5

分子式

C27H24O18

分子量

636.47

别名

1,3,6-Tri-O-galloyl-β-D-glucose;1,3,6-Tri-O-galloylglucose;1,3,6-三没食子酰葡萄糖;1,3,6-三-O-3,4,5-三羟基苯甲酰-BETA-D-葡萄糖

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years