Manassantin B is a potent inhibitor of NF-?oB activation by the suppression of transciptional activity of RelA/p65 subunit of NF-?oB. It also possesses anti-EBV lytic repliCATion activity. Manassantin B inhibits Interleukin-6-induced signal transducer and activator of transcription 3 activation in Hep3B cells, it has potential as a potent anti-inflammatory drug for use in pathological processes such as sepsis or acute lung injury. Manassantin B exerts antifibrotic activity in HSC-T6 cells, in part, via inhibition of cell proliferation and decrease of collagen production.

Manassantin B is a potent inhibitor of NF-IoB activation by the suppression of transciptional activity of RelA/p65 subunit of NF-IoB. It also possesses anti-EBV lytic replication activity. Manassantin B inhibits interleukin-6-induced signal transducer and activator of transcription 3 activation in Hep3B cells, it has potential as a potent anti-inflammatory drug for use in pathological processes such as sepsis or acute lung injury. Manassantin B exerts antifibrotic activity in HSC-T6 cells, in part, via inhibition of cell proliferation and decrease of collagen production.

88497-88-5

C41H48O11

716.81

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years