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Clematichinenoside AR
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Clematichinenoside AR图片
CAS NO:761425-93-8
包装与价格:
包装价格(元)
10 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
ClematichineNOSide AR 是从中药威灵仙中提取的一种天然产物,具有抗炎和免疫抑制特性,对 PI3K/Akt 信号通路和与胶原诱导的关节炎相关的 TNF-α± 具有抗关节炎作用。

产品描述

Clematichinenoside AR exerts anti-inflammatory and immunosuppressive properties, it has anti-arthritic effects on PI3K/Akt signaling pathway and TNF-α± associated with collagen-induced arthritis.

体外活性

C-AR was incubated with the content of the large intestine. The culture solution was collected at different time points and analyzed for the metabolites of C-AR. Eight metabolites were identified by liquid chromatography/quadrupole time-of-flight mass spectrometry. M1, M2 and M5 were the major metabolites. In addition, it was proposed that deglycosylation was the only pathway contributing to the biotransformation of C-AR in rat intestinal microflora.

Cas No.

761425-93-8

分子式

C82H134O43

分子量

1807.92

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years