Anemonin 是来自 Pulsatilla chinensis Regel 的天然产物。

Anemonin is a natural product from Pulsatilla chinensis Regel.

Human articular chondrocytes and cartilage explants challenged with interleukin-1β (IL-1β) were treated with Anemonin. Anemonin treatment attenuated proteoglycan loss in human cartilage explants treated with IL-1β ex vivo. Anemonin delayed articular cartilage degeneration in vitro[1].

Destabilization of the medial meniscus (DMM) was performed in 10-week-old male C57BL/6J mice. Anemonin was then intra-articularly injected into the joint capsule for 8 and 12 weeks. Anemonin delayed articular cartilage degeneration in vivo. Anemonin decre

90921-11-2

C10H8O4

192.17

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years