N-Methylflindersine 对盐水虾幼虫有很强的毒性,LD(50) 值为 1.39 microg/ml。它还展示了对 N-甲酰甲硫氨酰苯丙氨酸诱导的超氧化物产生的有效抑制作用,IC(50) 值小于 12 microM。
产品描述
N-Methylflindersine shows strong toxicity towards brine shrimp larvae, with an LD(50) value of 1.39 microg/ml. It also exhibits potent inhibition against N -formylmethionylleucylphenylalanine-induced superoxide production with IC(50) values less than 12 microM.
体外活性
Among the isolates, N-methylflindersine , (-)-simulanol , and evofolin-C exhibited potent inhibition against N-formylmethionylleucylphenylalanine-induced superoxide production with IC(50) values less than 12 microM[2].
Cas No.
50333-13-6
分子式
C15H15NO2
分子量
241.29
别名
2,2,6-Trimethyl-2H,5H-pyrano[3,2-c]quinolin-5-one;N-甲基芸香碱;2,2,6-trimethylpyrano[3,2-c]quinolin-5-one
储存和溶解度
DMSO:60 mg/ml (248.66 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years