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Oleanonic acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Oleanonic acid图片
CAS NO:17990-42-0
包装与价格:
包装价格(元)
20 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
3-Ketooleanolic Acid
3-Oxoolean-12-en-28-oic Acid
3-Oxooleanolic acid
齐墩果酮酸
产品介绍
Oleanonic acid是一种三萜,可以抑制 HIV-1 对细胞的感染。它具有保肝作用,并具有抗肿瘤和抗病毒特性。

产品描述

Oleanolic acid is relatively non-toxic, hepatoprotective, and exhibits antitumor and andantiviral properties.

激酶实验

Cerebral cortices from male Sprague-Dawley rats (200-300 g) are homogenized in 9 volumes of ice-cold 0.32mol/Lsucrose by nine strokes with a Teflon/glass homogenizer at 500 rpm. The homogenate is centrifuged for 10 min at 1×103 g, and the supernatant is recentrifuged at 1×104 g for 20 min at 4°C. The pellet is suspended in assay buffer (118 mM NaCl/4.7 mM KCl/1.2 mM MgSO4/5 mM NaHCO3/20 mM Hepes/1.2 mM KH2PO4/2.5 mM CaCl2/11 mM glucose, pH 7.4) and incubated at 23°C for 20 min prior to final centrifugation at 1×103 g for 20 min at 4°C. The pellet is resuspended in assay buffer (70 mL per gram of original tissue). Binding of [3H]MK-801 is measured by incubating 750 μL duplicate aliquots of this crude membrane suspension (=0.75 mg of protein) with 100 μL of buffer containing displacer or of buffer alone (total binding), 100 μL of 50 nM [3H]MK-801, and 50 μL of buffer for 60 min at 23°C. Nonspecific binding is defined by 100 μM (final concentration) unlabeled MK-801.

Cas No.

17990-42-0

分子式

C30H46O3

分子量

454.695

别名

3-Ketooleanolic Acid;Oleanonic Acid;3-Oxoolean-12-en-28-oic Acid;3-Oxooleanolic acid;齐墩果酮酸

储存和溶解度

DMSO:100 mg/mL (219.93 mM),Need ultrasonic
H2O:< 0.1 mg/mL (insoluble)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years