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Pristimerin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pristimerin图片
CAS NO:1258-84-0
包装与价格:
包装价格(元)
20 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
扁塑藤素
Celastrol methyl ester
产品介绍
Pristimerin是一种可逆的单酰基甘油脂肪酶高效抑制剂,IC50值为93 nM。

产品描述

1. Pristimerin has anticancer activity , treatment with Pristimerin may be a potential strategy for the suppression of hypoxia-induced metastasis through the reversal of hypoxia-induced stem cell characteristics and EMT in cancer cells. 2. Pristimerin down-regulates the expression of pro-inflammatory mediators through blocking of NF-κB activation by inhibiting interconnected ROS/IKK/NF-κB signaling pathways, can effectively inhibit both arthritic inflammation and cartilage and bone damage in the joints.

Cas No.

1258-84-0

分子式

C30H40O4

分子量

464.646

别名

扁塑藤素;Celastrol methyl ester

储存和溶解度

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years