Acetylcorynoline 是提取自Corydalis bungeana中的一种主要生物碱成分,具有抗炎活性。
产品描述
1. Acetylcorynoline has antifungal、anti-inflammatory activity. 2. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of dendritic cells maturation and function. 3. Acetylcorynoline is potential as a possible antiparkinsonian drug. (1) Significantly decreases dopaminergic neuron degeneration induced by 6-hydroxydopamine in BZ555 strain; (2) Prevents α-synuclein aggregation; (3) Restores food-sensing behavior, and dopamine levels; (4) Prolongs life-span in 6-hydroxydopamine-treated N2 strain. 4. Acetylcorynoline may exert its effects by decreasing egl-1 expression to suppress apoptosis pathways and by increasing rpn5 expression to enhance the activity of proteasomes.
Cas No.
18797-80-3
分子式
C23H23NO6
分子量
409.438
别名
O-Acetylcorynoline;乙酰紫堇灵;(+)-Corynoline Acetate
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years