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Fumaric acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:110-17-8
包装与价格:
包装价格(元)
50 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
2-Butenedioic acid
Trans-Butenedioic acid
反丁烯二酸
Fumarate
富马酸
Donitic acid
Lichenic acid
Allomaleic acid
产品介绍
Fumaric acid 与烟酸酶缺乏症相关,是癌症相关的内源性代谢物。

产品描述

Fumaric acid attenuates the eotaxin-1 expression in TNF-α-stimulated fibroblasts by suppressing p38 MAPK-dependent NF-κB signaling. Fumaric acid has recently been identified as an oncometabolite or an endogenous, cancer-causing metabolite. High levels of this organic acid can be found in tumors or biofluids surrounding tumors. Its oncogenic action appears due to its ability to inhibit prolyl hydroxylase-containing enzymes.

Cas No.

110-17-8

分子式

C4H4O4

分子量

116.1

别名

2-Butenedioic acid;Trans-Butenedioic acid;反丁烯二酸;Fumarate;富马酸;Donitic acid;Lichenic acid;Allomaleic acid

储存和溶解度

DMSO:21 mg/mL(180.9 mM)
Chloroform, Dichloromethane, Ethyl Acetate, Acetone:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years