Acetyl-trans-resveratrol 是 Resveratrol 的乙酰化类似物，可降低STAT3和NF-Κb磷酸化，具有抗癌作用。

Acetyl-trans-resveratrol has anti-cancer activity,it inhibits the phosphorylation of STAT3 and NFκB, down-regulates Mcl-1, and up-regulates Bim and Puma in pancreatic cancer cells.

Acetyl-trans-resveratrol inhibited cell viability, and induced apoptosis of pancreatic cancer cells in a concentration and incubation time-dependent manner[1].

Acetyl-trans-resveratrol significantly inhibited intracranial tumor growth and prolonged survival in these mouse models[2].

Apoptosis was determined by using apoptosis detection kit according to the manufacturers instructions.?Briefly, cells were treated with the indicated dosage of Acetyl-trans-resveratrol?for 48 h. The untreated and?treated cells were washed with PBS buffer and gently suspended in Annexin V binding buffer and incubated with Annexin V-FITC (20 μg/mL) and PI (20 μg/mL) for 15 minutes in the dark.?Flow cytometry analysis was performed using Cellquest software.

42206-94-0

C20H18O6

354.35

乙酰化白藜芦醇;Acetyl-trans-resveratrol;三乙酰基白藜芦醇

DMSO:50mg/m(141.24 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years