Podofilox 是从八角莲中分离的一种木脂素，是微管组装和DNA拓扑异构酶II抑制剂。它对皮肤和粘膜有很强的刺激性，具有角质溶解作用，可用于治疗疣和角化病，具有潜在的抗肿瘤特性。

Podophyllotoxin is a lignan (LIGNANS) found in PODOPHYLLIN resin from the roots of PODOPHYLLUM plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives.

518-28-5

C22H22O8

414.41

鬼臼毒素;Podophyllotoxin;(+)-Shikonin

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years