Butylphthalide 是一种抗脑缺血药物，最初分离自芹菜种中，对中风动物模型有效。

Butylphthalide is an anti-cerebral-ischemia drug; first isolated from the seeds of Apium graveolens Linn.

Butylphthalide alleviates oxidative stress caused by chronic cerebral ischemia, improves cholinergic function, and inhibits amyloid beta accumulation, thereby improving cerebral neuronal injury and cognitive deficits [1]. Intragastric NBP administration to 4-month-old SAMP8 mice for 2 months significantly improved spatial learning and memory ability. Moreover, the loss of choline acetyltransferase (ChAT)-positive neurons in the medial septal nucleus and the vertical limb of the diagonal band in SAMP8 mice was slowed down, as was the decline in the protein and mRNA expression of ChAT in the hippocampus, cerebral cortex, and forebrain [2].

6066-49-5

C12H14O2

190.242

丁基苯酞;3-Butylphthalide;3-n-Butylphthalide;3-n-Butylphathlide

DMSO:55 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years