Isobavachalcone 是来源于补骨脂的一种Akt信号通路抑制剂,可诱导人类癌细胞凋亡,以IC50值为 7.92 μM 抑制 OVCAR-8 癌细胞生长,具有抗癌和抗增殖活性。它还能诱导 OVCAR-8 细胞中活性氧的产生。
产品描述
Isobavachalcone is a chalcone constituent of Angelica keiskei, has potent anti-inflammatory activity, possible can ameliorate neuronal injury in brain diseases associated with inflammation.
Cas No.
20784-50-3
分子式
C20H20O4
分子量
324.376
别名
Isobacachalcone;Corylifolinin;补骨脂乙素
储存和溶解度
DMSO:58 mg/mL(178.8 mM)
Chloroform, Dichloromethane, Ethyl Acetate, Acetone:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years