3,4-Dihydroxyflavone 作为抗氧化剂和抗凋亡剂。
产品描述
3,4-Dihydroxyflavone Acts as an Antioxidant and Antiapoptotic Agent .
体外活性
Treatment with 3,4-DHF increased the ICM cell number and reduced intracellular ROS production and apoptotic cell numbers.?When O(2) tension was decreased from 20% (high tension) to 5% (low tension), embryo development rates were doubled regardless of 3,4-DHF treatment[1].
细胞实验
Blastocyst development, total cell and inner cell mass (ICM) numbers, intracellular levels of reactive oxygen species (ROS), apoptotic indices and gene expression levels were examined before and after treatment of day 2 bovine embryos (≥2-4 cells) with various concentrations of 3,4-DHF or SOD for 6 days[1].
Cas No.
4143-64-0
分子式
C15H10O4
分子量
254.241
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years