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Vinorelbine ditartrate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Vinorelbine ditartrate图片
CAS NO:125317-39-7
包装与价格:
包装价格(元)
20 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
Vinorelbine Tartrate
KW-2307
酒石酸长春瑞滨
长春瑞滨酒石酸盐
Navelbine tartrate
Nor-5'-anhydrovinblastine ditartrate
产品介绍
Vinorelbine Tartrate 是一种抗有丝分裂剂,能够抑制 Hela 细胞的增殖,IC50值为 1.25 nM。

产品描述

Vinorelbine Tartrate, a semi-synthetic vinca alkaloid, interacts with tubulin resulting in mitosis inhibition.

体外活性

Vinorelbine inhibits microtubule assembly by inducing tubulin aggregation into spirals and paracrystals. [1] Vinorelbine shows potent antiproliferative activity against a series of tumor cells, including human melanoma, non-small-cell lung cancer, breast cancer, etc. [2][3][4]

体内活性

In vivo, Vinorelbine also shows antitumour activity against a series of subcutaneously-implanted human tumour xenografts. [5]

Cas No.

125317-39-7

分子式

C53H66N4O20

分子量

1079.119

别名

Vinorelbine Tartrate;KW-2307;酒石酸长春瑞滨;长春瑞滨酒石酸盐;Navelbine tartrate;Nor-5'-anhydrovinblastine ditartrate

储存和溶解度

H2O:107.9 mg/mL (100 mM)
DMSO:107.9 mg/mL (100 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years