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Cyclo(Ile-Ala)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cyclo(Ile-Ala)图片
CAS NO:90821-99-1
包装与价格:
包装价格(元)
10 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
Cyclo(Ile-Ala) 是存在于海洋放线菌11014 I.中的天然产物。

产品描述

Cyclo(Ile-Ala) is a natural product.

体外活性

To find the cell cycle inhibitors from the metabolites of Streptomyces flavoretus 18522.METHODS AND RESULTS: Activity-guided isolation was performed on the chloroform extract of the fermentation broth and mycelia of Streptomyces flavoretus 18522 by using ts FT210 cells.Compounds were isolated through various chromatoghraphic methods and elucidated by spectroscopic means.The flow cytometry was used to evaluate the cell cycle inhibiting activity of the fractions and compounds. Six cyclic dipeptides were obtained and identified as cyclo(Ala-Leu)(1),Cyclo(Ile-Ala) (2),cyclo(Ala-Val)(3),cyclo(Phe-Leu)(4),cyclo(Ala-Pro)(5) and cyclo(Phe-Val)(6).CONCLUSIONS: Compounds 1-6 are reported as new cell cycle inhibitors for the first time.

Cas No.

90821-99-1

分子式

C9H16N2O2

分子量

184.24

储存和溶解度

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years