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Tetrahydrocannabivarin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tetrahydrocannabivarin图片
CAS NO:31262-37-0
包装与价格:
包装价格(元)
5 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
Tetrahydrocannavarin
CRM
THCV
delta9-Tetrahydrocannabivarin
产品介绍
Tetrahydrocannabivarin 是 cannabinoid type 1 receptor的中性拮抗剂,对 2 型糖尿病有潜在治疗价值。

产品描述

Tetrahydrocannabivarin is a neutral cannabis receptor subtype (CB1) receptor antagonist, it can increases neural responding to rewarding and aversive stimuli, this effect profile suggests therapeutic activity in obesity, perhaps with a lowered risk of depressive side effects. Tetrahydrocannabivarin exhibits anticonvulsant effects in a piriform cortical brain slice model of epileptiform activity.

体外活性

At 3-1000 nanomol (nM), THCV did not prevent electrically induced contractions of mouse isolated vas deferens; though, the amount of THCV in this range formed dextral shifts in the log concentration-response curves of WIN and anandamide for electrically evoked contractions. These changes were not convoyed by a reduction in the maximal effect of any agonist. Nevertheless, at 3 millimolar (mM), THCV did lessen the contractile reaction of the vas deferens in a CB1 receptor antagonist (SR141716)-independent way. Moreover, THCV looks like SR141716 antagonist, which at high quantities also cooperates with non-CB1 targets.[1].

Cas No.

31262-37-0

分子式

C19H26O2

分子量

286.41

别名

Tetrahydrocannavarin;CRM;THCV;delta9-Tetrahydrocannabivarin

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years