(2S)-6-Prenylnaringenin 是强效植物雌激素 8-prenylnaringenin 的异构体，是前脑中最有效的化合物，在 α+β 结合位点上起GABAA正变构调节剂的作用。

6-Prenylnaringenin is an isomer of the potent phytoestrogen, 8-prenylnaringenin. 6-Prenylnaringenin is the most potent compound in the forebrain and acts as a positive allosteric modulator of GABAA at the α+β binding site.

In native GABAA receptors, 6-Prenylnaringenin potentiates GABA-induced displacement of [3H]EBOB binding in a concentration-dependent manner with IC50s of 3.7 μM[1]. 6-Prenylnaringenin displays a modulatory activity at low micromolar concentrations.

68236-13-5

C20H20O5

340.37

6-Prenylnaringenin;6-PN;(2S)-6-异戊烯基柚皮素;6-异戊二烯基柚皮素

DMSO:95.30mg/mL(280mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years