Isorhamnetin 是从中草药沙棘中提取的一种类黄酮，可通过抑制MEK1和PI3K来抑制皮肤癌。

Isorhamnetin is the methylated metabolite of quercetin. Quercetin is an important dietary flavonoid with in vitro antioxidant activity. Isorhamnetin prevents endothelial cell injuries from oxidized LDL via inhibition of lectin-like ox-LDL receptor-1 upregulation, interference of ox-LDL-mediated intracellular signaling pathway (p38MAPK activation, NF-kappaB nuclear translocation, eNOS expression) and the antioxidant activity of isorhamnetin. Isorhamnetin prevents endothelial dysfunction, superoxide production, and overexpression of p47phox induced by angiotensin II. Isorhamnetin appears to be a potent drug against esophageal cancer due to it's in vitro potential to not only inhibit proliferation but also induce apoptosis of Eca-109 cells.

480-19-3

C16H12O7

316.265

3'-Methylquercetin;3-methylquercetin;异鼠李素;3'-Methoxyquercetin;Isorhamnetol

DMSO:28 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years