Crocin II 是从栀子果实中分离出来的一种天然产物，具有抗氧化、抗癌和抗抑郁活性。它抑制iNOS和COX-2的蛋白质和 m-RNA 的表达，还抑制NO产生，IC50值为 31.1 μM。

Crocin has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein expression of iNOS and caspase-3. Crocin can ameliorate CCl4-induced liver injury via inhibition of inflammatory cytokines, caspase3 and oxidative stress along with modulation of liver metabolizing enzymes favoring elimination of CCl4 toxic metabolite. Crocin has antihyperlipidemic effect, may be due to the inhibition of pancreatic lipase and crocin, and its metabolite, crocetin, can improve hyperlipidemia. Crocin has antidepressant effects by increasing CREB, BDNF and VGF levels in hippocampus.

55750-84-0

C38H54O19

814.831

Crocin B;西红花苷II;藏红花;Crocin 2;Crocetin gentiobiosylglucosyl ester;Tricrocin

DMSO:122.7 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years