RIP2 kinase inhibitor 1 (compound 11) is a highly potent and specific receptor interacting protein 2 (RIP2) kinase inhibitor with an IC50 of 0.03 μM for RIP2 FP. RIP2 kinase inhibitor 1 is used for autoinflammatory disorders. References: [1]. Haffner CD, et al. Discovery of Pyrazolocarboxamides as Potent and Selective Receptor Interacting Protein 2 (RIP2) Kinase Inhibitors.ACS Med Chem Lett. 2019 Oct 11;10(11):1518-1523.

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CAS：2380028-10-2