Boc-Asp(OME)-Fluoromethyl Keton 是广谱的 Caspase 抑制剂，可抑制 Fas 介导的吞噬作用和氧化破裂抑制，但对 IL-8 的趋化活性无影响。

Boc-Asp(OME)-Fluoromethyl Ketone is a broad range caspase inhibitor. Boc-Asp(OME)-Fluoromethyl Ketone inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemotactic activity of IL-8.

Boc-Asp(OME)-Fluoromethyl Keton (100 μM; 30 minutes; Polymorphonuclear leukocytes) prevents Fas-induced and spontaneous apoptosis (-CH-11)[1]. Boc-Asp(OME)-Fluoromethyl Keton (20 μM; 5 hours; J774.1/JA-4 cells) significantly increases the release of LDH[2].

187389-53-3

C11H18FNO5

263.265

Boc-Asp(OMe)-fluoromethyl ketone;Boc-Asp(OMe)-FMK

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years