1-Caffeoylquinic acid是一种有效的NF-Κb抑制剂,对 p105 的 RH 结构域显示高结合亲和力,Ki= 0.002 μM,结合能为 1.50 Kcal/mol。它抑制PD-1/PD-L1相互作用。它具有抗氧化应激能力。
产品描述
1-Caffeoylquinic acid is an important intermediate in lignin biosynthesis. 1-Caffeoylquinic acid has anti-influenza, and antioxidant activities, it also slows the release of glucose into the bloodstream after a meal.
体外活性
Thirteen phenolic compounds (3-caffeoylquinic acid, 5-caffeoylquinic acid, 1-Caffeoylquinic acid, 5-p-coumaroylquinic acid, isoorientin-2"-O-rhamnoside, isoorientin, orientin-2"-O-rhamnoside, orientin, 1-p-coumaroylquinic acid, vitexin-2"-O-rhamnoside, isovitexin-2"-O-rhamnoside, vitexin and isovitexin) were identified in T. hemsleyanum leaves for the first time, and six of them were quantified using a combination of LC-QTOF-MS and LC-QqQ-MS techniques. It was found that 80% methanol extract exhibited the highest antioxidant activities.
Cas No.
1241-87-8
分子式
C16H18O9
分子量
354.31
别名
金银花;1-咖啡酰奎宁酸
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years