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N-p-trans-Coumaroyltyramine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
N-p-trans-Coumaroyltyramine图片
CAS NO:36417-86-4
包装与价格:
包装价格(元)
5 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
N-反式对香豆酰基酪胺
N-反式-对香豆酰酪胺
产品介绍
N-p-trans-Coumaroyltyramine 是从蓼属植物中分离出的肉桂酰苯乙酰胺,是一种乙酰胆碱酯酶抑制剂,IC50 为 122 μM。它具有抗锥虫活性,对T. brucei Rhodesiense作用的 IC50值为 13.3 μM。

产品描述

N-p-trans-Coumaroyltyramine is a natural product, is an acetylcholinesterase (AChE) inhibitor with an an IC50 of 122 μM. N-p-trans-Coumaroyltyramine exhibits anti-trypanosomal activity with an IC50 of 13.3 μM for T. brucei rhodesiense.

体外活性

The methanolic extract of the twigs of Celtis chinensis was found to show inhibitory activity on acetylcholinesterase (AChE), an enzyme that plays a role in the metabolic hydrolysis of ACh. Bioassay-guided fractionation of the methanolic extract resulted in the isolation of N-p-trans-Coumaroyltyramine, as an inhibitor on AChE[1]

Cas No.

36417-86-4

分子式

C17H17NO3

分子量

283.32

别名

N-反式对香豆酰基酪胺;N-反式-对香豆酰酪胺

储存和溶解度

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years