Gypsogenin 是一种天然存在的生化物质，具有明显的抗血管生成活性和对 H460 的细胞毒性，拥有抗 ABL1 激酶和抗慢性骨髓性白血病作用。

Gypsogenin is a naturally occurring biochemical that shows anti-ABL1 kinase and anti-chronic Myelogenous Leukemia activities.

Gypsogenin (1) was obtained by acidic hydrolysis from its saponin.?While the parent compound 1 acted as a selective inhibitor for butyrylcholinesterase (from equus) possessing a moderate mixed-type inhibition of the enzyme, Ki values as low as 2.67 0.59 μM were determined for (3β,4α) 3-O-acetyl-olean-12-ene-23,28-dinitrile (11) and acetylcholinesterase (AChE, from electric eel).?Thus, 11 possesses one-fifth of the inhibitory activity of the "gold standard" galantamine hydrobromide;?this compound is one of the first pentacyclic triterpenoids described as a potent AChE-selective inhibitor

639-14-5

C30H46O4

470.68

639-14-5;丝石竹皂苷元

DMSO:27.5 mg/ml (58.42 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years