Naringin是一种黄烷酮糖苷,有抗氧化活性、降血脂、抗癌和抑制细胞色素P450酶的药理作用。
产品描述
Naringin, a flavanone glycoside, exerts various of pharmacological effects such as blood lipid lowering, antioxidant activity, anticancer activity, and inhibition of cytochrome P450 enzymes.
体内活性
The Lethal Dose 50 for mice:1650 mg/kg.
细胞实验
HBZY-1 cells are plated into 96-well plates and pretreated with various concentrations(1, 5, 10, 25, 50, 100 μM) of naringin for 2 h. Then cells are treated with 30 mM glucose for 24 h. The control group is added sterile normal saline in the same volume. After treatment, all the wells are incubated with 20 μL of 5 mg/ml MTT for 4 h at 37°C. Subsequently, 100 μL of DMSO are used to dissolve the formed formazan crystals after removal of the supernatant. The result is recorded at 490 nm on a microplate reader[1].
Cas No.
10236-47-2
分子式
C27H32O14
分子量
580.539
别名
Naringoside;柚皮苷
储存和溶解度
Ethanol:1 mg/mL (1.7 mM)
H2O:<1 mgml
DMSO:91 mg/mL(156.8 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years