Kasugamycin hydrochloride 是一种能结合 30s 和 70s 核糖体,但不能结合 50s 亚基的抗生素。它模拟 mRNA 核苷酸以破坏 tRNA 结合并抑制经典翻译起始。
产品描述
Kasugamycin (Ksg) is an aminoglycoside antibiotic that was originally isolated in 1965, from Streptomyces kasugaensis, a Streptomyces strain found near the Kasuga shrine in Nara, Japan. Kasugamycin was discovered by Hamao Umezawa, who also discovered kanamycin and bleomycin, as a drug which could prevent growth of a fungus causing rice blast disease.
Cas No.
19408-46-9
分子式
C14H26ClN3O9
分子量
415.82
别名
盐酸春雷霉素;Kasumin
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years