SenNOSide A 是在番泻叶的叶子和豆荚中大量发现的蒽醌苷,抑制 HIV-1 复制。
产品描述
Sennoside A, a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine.
体外活性
Sennoside A, a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine through regulating the spontaneous motility of colon. [2] It mildly inhibits bovine serum monoamine oxidase with IC50 of 17 μM. [1]
体内活性
LD50: Mice 5000 mg/kg (i.g.); Rats 5000 mg/kg (i.g.). [3]
Cas No.
81-27-6
分子式
C42H38O20
分子量
862.746
别名
NSC 112929;番泻苷A;番泻苷 A
储存和溶解度
H2O:<1 mgml
Ethanol:<1 mgml
DMSO:95 mg/mL (110.1 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years