Magnolin 是辛夷的一种主要成分，靶向作用于ERK1和ERK2，IC50值分别为 87 和 16.5 nM，可抑制Ras/ERKs/RSK2信号通路。它在体内外降低肾脏氧化应激，抑制 Caspase-3 活性，并增加 BCL-2 表达，具有抗炎和抗氧化作用。

Magnolin reduces the renal oxidative stress, suppresses caspase-3 activity, and increases Bcl-2 expression in vivo and in vitro. Magnolin has anti-inflammatory and antioxidative effects.

31008-18-1

C23H28O7

416.47

木兰脂素;木兰苷;(+)-Magnolin

Chloroform, Dichloromethane, Ethyl Acetate:Soluble
DMSO:75 mg/mL(180.1 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years