Deoxylapachol 是新西兰褐藻Landsburgia quercifolia的主要细胞毒性成分,有抗真菌和抗癌活性。
产品描述
Deoxylapachol has anti-wood rot activity, it can inhibit the brown rot fungi Gloeophyllum sepiarium CBS 353.74 and Gloeophyllum trabeum CBS 318.50 and the white rot fungi Merulius tremellosus CBS 280.73 and Phlebia brevispora CBS 509.92. It also can induce fungal cell wall stress.
体外活性
Teak ( Tectona grandis L.f., Verbenaceae) sawdust extract inhibited the growth of Aspergillus niger. By (1)H-NMR the active compounds were identified as Deoxylapachol and tectoquinone. Two A. niger transgenic strains which show induction of 1,3 -alpha-D-glucan synthase were used as a cell wall damage model[1]. Deoxylapachol is active against P-388 leukemia cells with IC50 of 0.6 microgm/ml).
Cas No.
3568-90-9
分子式
C15H14O2
分子量
226.27
储存和溶解度
DMSO:95 mg/mL (419.85 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years