5-Deoxystrigol 是一种高活性的独脚金发芽刺激剂。对D-半乳糖胺(D-GalN)诱导的小鼠急性肝损伤有保护作用,对CCl4诱导的小鼠急性肝损伤有保护作用。
产品描述
5-Deoxystrigol is a highly active Striga germination stimulant. It has a protective effect on D-galactosamine (D-GalN) induced mice acute liver injury and has a protective effect on CCl4 induced mice acute liver injury.
体外活性
Striga is a major biotic constraint to sorghum production in semiarid tropical Africa and Asia. Genetic resistance to this parasitic weed is the most economically feasible control measure. Mutant alleles at the LGS1 (LOW GERMINATION STIMULANT 1) locus drastically reduce Striga germination stimulant activity. METHODS AND RESULTS: We provide evidence that the responsible gene at LGS1 codes for an enzyme annotated as a sulfotransferase and show that functional loss of this gene results in a change of the dominant strigolactone (SL) in root exudates from 5-Deoxystrigol, a highly active Striga germination stimulant, to orobanchol, an SL with opposite stereochemistry. Orobanchol, although not previously reported in sorghum, functions in the multiple SL roles required for normal growth and environmental responsiveness but does not stimulate germination of Striga. CONCLUSIONS: This work describes the identification of a gene regulating Striga resistance and the underlying protective chemistry resulting from mutation.
Cas No.
151716-18-6
分子式
C19H22O5
分子量
330.38
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years