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Bruceine B
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Bruceine B图片
CAS NO:25514-29-8
包装:1 mg
市场价:3850元

产品介绍
Bruceine B 是一种有效的白细胞-内皮细胞粘附抑制剂,可抑制蛋白质和核酸合成。

产品描述

Bruceine B, a potent inhibitor of leukocyte-endothelial cell adhesion, may have anti-inflammatory activity, it can inhibit neutrophil adhesion to lipopolysaccharide-stimulated HUVEC and T cell adhesion to TNF-stimulated HUVEC.

体内活性

Leukocyte adhesion to vascular endothelial cells is an essential step in the development of inflammatory diseases.??inhibitors of leukocyte-endothelial cell adhesion that could be used as anti-inflammatory drugs and found that bruceine B (0.2 microgram/ml;?0.44 microM) inhibited human neutrophil or T cell adhesion to tumor necrosis factor-alpha (TNF) stimulated human umbilical vein endothelial cells (HUVEC).

Cas No.

25514-29-8

分子式

C23H28O11

分子量

480.466

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years