Molnupiravir (EIDD-2801) 是核糖核苷类似物 EIDD-1931 的口服生物可利用的异丙酯前药。Molnupiravir 显示出广泛的抗流感病毒 (Influenza Virus) 和coronaviruses的活性，如 SARS-CoV-2，MERS-CoV，SARS-CoV。Molnupiravir 有用于 COVID-19 和季节性，流行性流感的潜力。

Molnupiravir (EIDD-2801) is an orally bioavailable prodrug of the ribonucleoside analog EIDD-1931. Molnupiravir has broad spectrum antiviral activity against Influenza Virus and multiple coronaviruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV. Molnupiravir has the potential for the research of COVID-19, and seasonal and pandemic influenza.

Molnupiravir (50-500 mg/kg; p.o.; every 12 hours for 3 days) is robustly antiviral and able to prevent SARS-CoV replication and disease[1]. Molnupiravir (7 mg/kg; p.o.; twice daily for 3.5 days) significantly reduces shed virus load and duration of fever[2].

2492423-29-5

C13H19N3O7

329.31

Lagevrio;MK-4482;EIDD-2801

DMSO:45mg/mL (136.6mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years