Ethylparaben 是一种标准化的化学过敏原。 对羟基苯甲酸乙酯的生理作用是通过增加组胺释放和细胞介导免疫来实现的。

Ethylparaben is a Standardized Chemical Allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity.

Ethylparaben has weak estrogenic and weak anti-androgenic effects in vitro[2].

In vivo studies indicate that ethylparaben has estrogenic effects in vivo in immature and ovariotectomized mice. A study on fetal exposure to ethylparaben revealed no changes in male anogenital distance and no changes of fetal testosterone production, but changes in gene expression levels pointed to subtle endocrine disrupting effects. A limited study in young male rats found no adverse effects, although tendencies to lower sperm counts are seen. Ethylparaben causes vitellogenin induction in fish[2].

120-47-8

C9H10O3

166.17

羟苯乙酯;Ethyl parahydroxybenzoate;尼泊金乙酯;Ethyl 4-hydroxybenzoate

DMSO:31 mg/mL (186.6 mM)
H2O:<1 mgml
Ethanol:31 mg/mL (186.6 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years