N-trans-caffeoyltyramine 是炎症反应的调节剂,可用于慢性炎症性疾病治疗的研究。
产品描述
N-trans-caffeoyltyramine is a modulator of inflammatory responses and can be used in studies about treatment for chronic inflammatory diseases.
体外活性
N-trans-caffeoyltyramine inhibits the production of NO, TNF-α, IL-6 and IL-10 in the LPS-stimulated RAW 264.7 cells in a dose-dependent manner. N-trans-caffeoyltyramine markedly suppresses the expression of COX-2 and the production of prostaglandin E2 (PGE2) in response to LPS stimulation. N-trans-caffeoyltyramine markedly decreases p-c-Jun N-terminal kinase (p-JNK) protein expression in LPS-stimulated RAW 264.7 cells[1].
Cas No.
103188-48-3
分子式
C17H17NO4
分子量
299.32
别名
N-(E)-Caffeoyl-lambda-tyramine;Typheramide;Trans-N-Caffeoyltyramine;N-cis-Caffeoyltyramine
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years