(S,S,S)-AHPC hydrochloride 是 von Hippel-Lindau (VHL) 氨基砌块。(S,S,S)-AHPC (Compound 27) 常作为 (S,R,S)-AHPC 的阴性对照。(S,R,S)-AHPC 是基于 VH032 的 VHL 配体，可用于募集 VHL 蛋白。

(S,S,S)-AHPC hydrochloride is a VHL amino building block, is a ligand used as a negative control for (S,R,S)-AHPC. It is the VH032-based VHL ligand used in the recruitment of the VHL protein.

VHL is one of the most popular E3 ligases being recruited by bifunctional Proteolysis-targeting chimeras (PROTACs) to induce ubiquitination and subsequent proteasomal degradation of a target protein.

2115897-23-7

C22H31ClN4O3S

467.03

(S,S,S)-AHPC盐酸盐;(S,S,S)-VH032-NH2 hydrochloride

H2O:99 mg/mL (211.98 mM),Need ultrasonic
DMSO:60 mg/mL (128.47 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years