m-PEG24-NH2 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。
产品描述
m-PEG24-NH2 is a PEG-based PROTAC linker. m-PEG24-NH2 can be used in the synthesis of PROTACs.
体外活性
PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
2151823-08-2
分子式
C49H101NO24
分子量
1088.32
别名
氨基二十四甘醇单甲醚
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years